منابع مشابه
From the Egg-Yolk to the Scrambled-Egg Theory
The way we deal with space in many everyday situations is on a qualitative basis, allowing for imprecision in spatial descriptions when we interact with each other. This is often achieved by specifying the spatial relations between the objects or regions that we talk about. In artificial intelligence, a variety of formalisms have been developed that deal with space on the basis of relations bet...
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The recent surge of interest in oocyte development has been spurred in large part by the increasing implementation of assisted reproductive technologies (ART) to treat human infertility. What is becoming apparent is that 'egg quality' is a primary factor in the success of ART (Sauer 1998), and yet we know virtually nothing about the molecular signature of a 'high quality' oocyte, i.e., an oocyt...
متن کاملEngineered nanomaterial uptake and tissue distribution: from cell to organism
Improved understanding of interactions between nanoparticles and biological systems is needed to develop safety standards and to design new generations of nanomaterials. This article reviews the molecular mechanisms of cellular uptake of engineered nanoparticles, their intracellular fate, and their distribution within an organism. We have reviewed the available literature on the uptake and disp...
متن کاملBiological models for phytochemical research: from cell to human organism.
Nutrigenomics represents a shift of nutrition research from epidemiology and physiology to molecular biology and genetics. Nutrigenomics seeks to understand nutrition influences on homeostasis, the mechanism of genetic predispositions for diseases, to identify the genes influencing risk of diet related diseases. This review presents some in vitro models applicable in nutrigenomic studies, and d...
متن کاملProtein folding in the cell, from atom to organism.
Proper cell function requires proper protein folding. Misfolding of specific proteins, caused either by mutation or environmental stress, underlies many human diseases, including cancer and diabetes and Parkinson’s, Huntington’s, and Alzheimer’s disease. Protein folding has been studied for decades in the test tube, initially spearheaded by the classical studies of Anfinsen and colleagues (1). ...
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ژورنال
عنوان ژورنال: Development
سال: 2003
ISSN: 1477-9129,0950-1991
DOI: 10.1242/dev.00787